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Inspra is a prescription strength medicine that can be taken alone or combined with other drugs to treat hypertension (high blood pressure). Having high blood pressure is usually a surprising diagnosis during a medical exam because you feel fine and had no idea that your heart was working hard to try and pump a healthy supply of blood around to other organs and tissues. If left undiagnosed or untreated, hypertension can lead to strokes, heart attacks, and kidney problems.
Inspra is a potassium-sparing diuretic and when taken as directed will work by blocking a specific hormone in your body called Aldosterone, resulting in a decrease in the amount of sodium and water your body retains by increasing your urine output. So excess fluid is decreased but without affecting potassium levels. Less fluid in your bloodstream means a lower blood pressure. Inspra or Eplerenone generic have also been prescribed for patients with severe to moderate systolic heart failure. The generic alternative is not manufactured by the company that makes the brand product.
Aldosterone is a hormone released by the adrenal glands and helps the body regulate blood pressure. Aldosterone increases the reabsorption of sodium and water and the release of potassium in the kidneys. This action raises blood pressure. Aldosterone is involved in the development and progression of heart failure, including heart failure that can occur following a heart attack.
Heart failure is the inability of your heart to pump normally after it is damaged or weakened by certain medical conditions. If your heart is not strong enough to pump an adequate supply of blood to your other organs, excess fluid can build up in your lungs and other parts of your body. By blocking Aldosterone, the changes in the body that lead to worsening of heart failure and the symptoms fatigue and difficult breathing are reduced.
Some medicines can interact with Inspra and should not be used at the same time. Advise your doctor if you take Nefazodone, Verapamil, a diuretic or "water pill," an antibiotic or antifungal medication, HIV or AIDS medicines, hepatitis C medication, or other heart or blood pressure medications. If you are still of childbearing age, ask your doctor about any risk to your unborn or nursing baby.
You may feel dizzy when taking this medication. You should not drive or perform any tasks which may be dangerous until you determine how Inspra affects you. Potassium levels in your blood may be affected while taking this medication so have your blood tested regularly as directed by your doctor. All medications should be stored safely out of children’s reach and never share any meds with anyone else.