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Lodine SR (sustained release) or generic Etodolac SR is a non-steroidal anti inflammatory drug (NSAID) that is prescribed to treat acute and chronic arthritic conditions, such as osteoarthritis and rheumatoid arthritis. This NSAID may be a better choice of a long-term medication for relieving painful inflammation so you are able to complete your daily tasks in comfort with a reduced risk of side effects. The generic alternative is not manufactured by the company that makes the brand product.
Many NSAIDs inhibit both the COX-1 and COX-2 (cyclo-oxygenase) enzyme in order to stop or reduce the production of prostaglandins. When there is a threat, whether real or perceived, prostaglandins are the inflammatory chemicals your body sends to contain the danger while white bloods cells flood the area to start the healing process.
It has been found, however, that Lodine SR or generic Etodolac SR shows selective COX-2 inhibition and COX-1 sparing effects. This means you are less likely to have stomach problems because the COX-1 enzymes are able to help maintain the mucus lining in your stomach so the acid cannot cause any scarring or damage.
Osteoarthritis (OA) is a joint disease that causes the breakdown of cartilage, bone to overgrow, and cysts to form, usually in your hands, feet, hips, knees, and spine. Cartilage is the protective covering in your joints that prevents the bones from rubbing against each other. For those dealing with OA, the cartilage is destroyed from normal wear and tear. This friction can cause debilitating pain and inflammation and can stop you from enjoying even the simplest activities.
Rheumatoid arthritis (RA) occurs when your own immune system mistakes your body tissues for a foreign intruder and begins sending prostaglandins and other chemicals to take care of the threat. Most of the damage is to your joint lining and cartilage so your bones begin to rub against each other. RA usually affects the fingers, wrists, knees, and elbows so that even small chores such as opening a lid, lifting, or picking up objects can be painful. RA can occur in people as young as 20 years old.
Tell your doctor if you are pregnant, may become pregnant, or are breast feeding as Lodine SR may not be safe for your unborn or nursing baby. Discuss other health concerns you have and list any current OTC or Rx medications you are taking, including any vitamin or herbal supplements. Your doctor will then determine if Lodine SR is the right medication for you.
Lodine SR contains lactose, so you should tell your doctor if you are intolerant of certain sugars. Until you know how Lodine SR will affect you, avoid driving or performing any risky activities. Once you have the pain and inflammation under control, your doctor may recommend a lower dose of Lodine SR for long-term use to reduce the risk of harmful side effects.