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Quick Overview

Relafen (Nabumetone)

Relafen (Nabumetone)

Product Name Price Qty    
500mg Tablet

(℞) Prescription required.

Generic equivalents for Relafen

500mg Tablet

(℞) Prescription required.

Availability: In stock



Relafen Provides Relief from Arthritis Pain

Relafen is a nonsteroidal anti-inflammatory drug (NSAID) that may be prescribed to help reduce the joint stiffness and pain associated with osteoarthritis (OA) and rheumatoid arthritis (RA). Osteoarthritis is the most common form of arthritis that usually affects the hips, knees, hands, feet, and your spine that occurs as a result of being overweight, repeated injury to the joint whether through your job or sports, and increasing age. Rheumatoid arthritis is referred to as an autoimmune disease that causes your body’s immune system to attack your own tissues, such as joint lining and cartilage.

How Relafen Works to Reduce Arthritis Symptoms

Relafen and the generic called Nabumetone works by blocking an enzyme, called cyclooxygenase-2 (COX-2), that is responsible for producing prostaglandins, a type of hormone that promotes inflammation, pain, and even fever as a way to start healing, with less effects on COX-1 which is responsible, in part, for maintaining your stomach lining. This results in less problems that involve ulcers and bleeding.

Conditions Treated by Relafen

Rheumatoid arthritis, ankylosing spondylitis, and juvenile arthritis are some common examples of autoimmune conditions that can result in painful swelling and the inflammation of joints. An autoimmune disease is basically your immune system stuck in the “ON” position. There is no cure for arthritis, but taking Relafen will help manage your discomfort and allow you to carry out your daily tasks.

Before You Take Relafen

Relafen may cause or worsen cardiovascular problems, so your doctor should know whether you have a history of heart disease, stroke, or blood clot before you start taking it. List any current OTC or Rx drugs you take, including herbal remedies and dietary or vitamin supplements so it can be determined if Relafen is the right medication for you.

Precautions for Relafen

Be sure to avoid certain cold and allergy drugs during treatment, as they may lead to negative interactions and more severe side effects. Take these and other medications only under the direction of your doctor. Taking Relafen or generic Nabumetone long-term can cause other side effects so your doctor may only recommend taking it when your joint pain and swelling is bad.

If you are scheduled for any dental or surgical procedures, inform the medical staff you are taking Relafen as you may need to stop taking it for a time before or after these events are planned.

Possible Side Effects of Relafen

  • Stomach upset including diarrhea or constipation
  • Heartburn
  • Dizziness
  • Headache
  • Skin irritation
  • Vision problems