DABRAFENIB (da braf e nib) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat melanoma, non-small cell lung cancer, and thyroid cancer.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions: -diabetes -G6PD deficiency -liver disease -an unusual or allergic reaction to dabrafenib, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after food. Do not take with food. Do not take with grapefruit juice. Do not cut, crush, or chew this medicine. Avoid taking H2 blockers or antacids within 2 hours of taking this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.
This medicine may interact with the following medications: -clarithromycin -dexamethasone -female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections -gemfibrozil -grapefruit juice -ketoconazole -midazolam -nefazodone -warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor or health care professional for regular checks on your progress. Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine. Tell your doctor or health care professional right away if you have any change in your eyesight. Do not become pregnant while taking this medicine or for 2 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after stopping it. This medicine may interfere with the ability to have a child. You should talk with your doctor or health care professional if you are concerned about your fertility.
Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -changes in vision -dizziness -eye pain -fever -increased thirst -increased urination -redness, swelling, or sores on hands or feet Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): -headache -joint pain -hair loss
This list may not describe all possible side effects. Call your doctor for medical advice about side effects.
Store between 20 and 25 degrees C (68 and 77 degrees F). Your healthcare provider or pharmacist should throw away any unused medicine after the expiration date. Keep out of the reach of children.